Conference

Submitted abstracts from CMROI members.

ISMRM 2013

Haris et al. “High Resolution Mapping of Modafinil Induced Changes in Glutamate Level in Rat Brain”.

Crescenzi, R., et al. “Glutamate Changes in a Mouse Model of Tauopathy”.

Singh A, et al., “Z-Spectrum Fitting for CEST Contrast Computation in In Vivo Myocardium Tissue”.

Kogan F, Stafford R, Haris M, Englund E, Singh A, Cai K, Debrosse C, Nanga RP, Hariharan H, Detre J, Reddy R. “Contribution of tissue perfusion to the cest effect from creatine in skeletal muscle”.

Cai K, Haris M, Singh A, Nanga RP, Ittyerah R, Reddy D, Poptani, H, Hariharan H, Reddy R. “CEST effect at 2ppm (CEST@2ppm): a potential biomarker for grading brain tumor malignancy”.

Cai K, Singh A, Haris M, Nanga RP, Ittyerah R, Reddy D, Poptani, H, Hariharan H, Reddy R. “Z Spectral analysis for the quantification of multiple slow-exchanging metabolites”.

Ravi Prakash Reddy Nanga, Hari Hariharan, Ravinder Reddy. “An Alternate Strategy for the Quantification of the in vivo Glutamate/Glutamine (Glx) Peak at 2.35 ppm”.

Wang Z, Das S, Wolk D, Detre JA, “Assessing Arterial Spin Labeled Perfusion MRI as an Early-Alzheimer’s Disease Marker using the ADNI 2 data”.

Zhang Y, Wang Z, “Arterial spin labeling (ASL) denoising with Markov random field (MRF) optimization”.

Stafford RB, Oh SH, Woo MK, Zhao T, Kim KN, Kim YB, Cho ZH, Detre JA, Lee J, “Active Head Coil Detuning: A Method to Reduce SAR in CASL at 7T.

Woo MK, Stafford RB, Hong SM, Oh SH, Kim YB, Lee J, Cho ZH, “Detunable RF Coil for Arterial Spin Labeling at 7T”.

Oh SH, Lee J, Background-Suppressed Myelin Water Imaging”.

Liu SH, Kim D, Stafford RB, Oh SH, Park SH, Wang DJJ, Wang Z, Han M, Detre JA, Lee J, “Improving ASL using 3D bSSFP with Background Suppression and Two-dimensional GRAPPA”.

Oh SH, Lee J, “Origin of B0 orientation dependent R2* (=1/T2*) in white matter: magic angle effect vs. magnetic susceptibility”.

Oh SS, Oh SH, Park HW, Lee J, “An Improved Susceptibility Weighted Imaging Method using Multi-Echo Acquisition”.

R. X. Smith, L. Yan, S. Rapacchi, Y. Xue, S. Srinivasan, D. Ennis, P. Hu, H. K. Song, D. J. J. Wang, “Ultrafast Non-Contrast Enhanced 4D Dynamic MRA with 3D Stack-of-Stars Golden Angle Radial Acquisition and KWIC Reconstruction”.

J. Yu, Y. Xue, H. K. Song, “Accelerating Compressed Sensing Based DCE-MRI Image Reconstruction with GPU”.

OARSI 2013

Singh A, et al, “High Resolution T1ρ Mapping of Human Knee Cartilage at 7T MRI”.

SPIE Photonics West, 2013

Choe, R.; Busch, D. R.; Durduran, T.; Giammarco, J. M.; Pathak, S.; Chung, S. H.; Ban, H. Y.; Foster, E. K.; Averna, T.; Jung, K. W.; Carlile, P. M.; Buckley, E. M.; Kim, M. N.; Putt, M. E.; Mies, C.; Schnall, M. D.; Rosen, M. A.; DeMichele, A. & Yodh, A. G. “Early prediction of neoadjuvant chemotherapeutic efficacy with multi-parametric diffuse optical methods”.

Han Y Ban, Manabu Machida, David R Busch, Frank Moscatelli, Saurav Pathak, John C Schotland, Vadim A Markel, Arjun G Yodh. “Mitigating the effects of the chest wall boundary in Diffuse Optical Tomography”.

Jennifer M. Lynch, Erin M. Buckley, Peter Schwab, Brian D. Hanna, Daniel J. Licht, Arjun G. Yodh, “Validation of optically measured cerebral venous oxygen saturation in humans”.

So Hyun Chung, Keith A. Cengel, Charles B. Simone, Joseph S. Friedberg, Steven M. Albelda, Madeline E. Winters, Julien Menko, Jarod C. Finlay, Timothy C. Zhu, Eli Glatstein, Arjun G. Yodh, Theresa Busch, “Cytokine-reported inflammation after pre-PDT tumor excision is correlated with PDT-induced hypoxia measured by diffuse optical spectroscopy in mesothelioma patients”.

So Hyun Chung, Hon Yu, Min-Ying Su, Albert E. Cerussi, Bruce J. Tromberg, Chung Choe, Arjun G Yodh, “A Portable and Simple Method for Noninvasive Tissue Pathology”.

Annual Neurocritical Care Society Meeting 2013

M.Chandra, S. Park, R. Mesquita, K. Propert, S. Schenkel, D. Minkoff, S. Frangos, A.G. Yodh, W Andrew Kofke, “Autoregulation Assessment by Continuous Noninvasive Cerebral Blood Flow Monitoring”.

American Heart Association’s Scientific Sessions 2013

Jennifer M Lynch, Erin M Buckley, Peter J Schwab, David Busch, Rui Xiao, Ann L McCarthy, Susan C Nicolson, Lisa M Montenegro, Stephanie Fuller, J. William Gaynor, Thomas L Spray, Arjun G Yodh, Maryam Y Naim, Daniel J Licht, “Time-to-Surgery Predicts Postoperative Ischemic Injury in Hypoplastic Left Heart Syndrome”

XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function 2013

Jennifer M. Lynch, Erin M. Buckley, Peter Schwab, M.E. Putt, Brian D. Hanna, Daniel J. Licht, Arjun G. Yodh, “Validation of Optically Measured Cerebral Venous Oxygen Saturation in Humans”.

Jennifer M. Lynch, Erin M. Buckley, Peter Schwab, Michael Feldman, Matthew Harris, Daniel J. Licht, Arjun G. Yodh, “Cerebral Blood Flow Response of Intravenous Adenosine Infusion”.

ISMRM 2012

Nanga, R., Roalf, D., Cai, K., Elliott, M., Hariharan, H., Loughead, J., Poptani, H., Reddy, R., and Gur, R.  Magnetic Resonance Spectroscopy of the Deep Brain Structures at 7.0T, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 1803.

Singh, A., Haris, H., Cai, K., Babu, V., Kogan, F., Hariharan, H., and Reddy, R.  CEST MRI of Human Knee Cartilage at 3T and 7T, Proc. Intl. Mag. Reson. Med. 20, (2012). P.3370.

Singh, A., Cai, K., Haris, M., Hariharan, H., and Reddy, R.  B1 Inhomogeneity Correction of In-vivo CEST Contrast, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 4186.

Fenty, M., Shah, R., Kuang, Y., Stambough, J., Kelly, J., Reddy, R., and Tjoumakaris, F.  Quantification of Longitudinal Changes in Cartilage Following Viscosupplementation Therapy Via T MRI, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 1380.

Cai, K., Singh, A., Haris, M., Nanga, R., Hariharan H., and Reddy, R.  Imaging of Regional Distribution of Brain Glutamate with GluCEST MRI, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 3377.

Haris, M., Cai, K., Singh, A., Nanga, R., Reddy, C.D., Hariharan, H., and Reddy, R.  Detection of Exercised Induced Changes in Creatine Level in Human Calf Muscles through CEST: A Preliminary Study, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 2342.

Cai, K., Nanga, R., Lamprou, L., Schinstine, C., Meeks, J., Elliott, M., Hariharan, H., Reddy, R., and Epperson, N.  7T MRS of Brain GABA Pre and Post Gabapentin Administration in Healthy Males, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 3149.

Chilakapati, S., Reddy, S., Haris, M., Singh, A., Cai, K., Nath, K., Hariharan, H., and Reddy, R. Characterization of CEST effect from Glucose In Vitro, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 2335.

Kogan, F., Singh, A., Haris, M., Cai, K., Hariharan, H., and Reddy, R.  Chemical Exchange Contrast with Off-Resonance Spin Locking, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 4192.

Kogan, F., Singh, A., Haris, M., Cai, K., Hariharan, H., and Reddy, R.  Imaging of Glutamate in the Spinal Cord using Chemical Exchange Saturation Transfer  (CEST) at 7T, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 737.

Cai, K., Xu, H.N., Haris, M., Singh, A., Reddy, R., and Li, L.Z.  CEST MRI as a Potential Imaging Biomarker of Mitochondrial Metabolic State of Breast Cancer, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 3378.

Haris, M., Singh, A., Cai, K., Nanga, R.P.R., Debrosse, C., Hariharan, H., and Reddy, R.  Chemical Exchange Saturation Transfer Effects from Creatine Kinase Reaction Metabolites, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 2343.

Pilkinton, D.T. and Reddy, R.  Dependence of Cerebral Blood Flow and Oxygen Consumption on Hyperoxia-Induced Changes in the Longitudinal Relaxation Time, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 2911.

Haris, M., Nath, K., Singh, A., Cai, K., Nelson, D., Leeper, D.B., Hariharan, H., Glickson, J.D., and Reddy, R. Evaluation of Melanoma Xenograft Through CEST Imaging: A Preliminary Report, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 1518.

Pilkinton, D., Babu, V.K., Baker, W., Greenberg, J.H., and Reddy, R.  Hyperoxic Calibrated Quantitative fMRI for the Measurement of Regional Cerebral Metabolic Rate of Oxygen in a Hypermetabolic Swine Model, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 2912.

Cai, K., Xu, H.N., Singh, A., Haris, M., Reddy, R., and Li, L.Z.  Imaging of Prostate Cancer Metabolic Heterogeneity with CEST and MT MRI, Proc. Intl. Mag. Reson. Med. 20, (2012), p. 181.

AAOSM 2012

Fenty, M, et al., “Viscosupplementation Improves Short-term Proteoglycan Content in Superficial Knee Cartilage by T1p MRI:  Implications for Disease Modifying Capacity”.

OARSI 2012

Fenty M., et al., “Longitundinal evaluation of viscosupplementation therapy on OA patients using T1p MRI”.

ORS 2012

Fenty, M., et al., “Intra-articular Viscosupplementation improves protoeglycan content in superficial knee cartilage by T1p MRI”.

NEUROSCIENCE 2012

Sheila Shanmugan, Ravi Prakash Reddy Nanga, Hari Hariharan, Mark Elliott, Jeanette Bradley, Claudia Schnistine, Ravinder Reddy, C. Neill Epperson. “Psychostimulant Treatment Effects on Prefrontal Brain Activation, Glutamate Concentration and Executive Function in Menopausal Women with Memory Complaints”.

fNIRSCOnference

Meeri N. Kim, Matthew R. Sanborn, Mark E. Edsell, Rickson C. Mesquita, Mary E. Putt, Chris Imray, Heng Yow, Mark Wilson, Daniel S. Martin, Mike Grocott, Arjun G. Yodh, “Cerebral Hemodynamics at Altitude: Effects of Hyperventilation and Acclimatization on Cerebral Blood Flow and Oxygenation”.

OSA Biomedical Topical Meeting 2012

Busch, David R.; Guo, W.; Choe, R.; Durduran, T.; Feldman, M. D.; Mies, C.; Czerniecki, B. J.; Tchou, J.; DeMichele, A.; Schnall, M. D.; Rosen, M. A. &Yodh, A. G. “Computer Aided Monitoring of Neoadjuvant Chemotherapy for Breast Cancer”.
Busch, David R.; Choe, R.; Durduran, T.; Baker, W.; Foster, E. K.; Friedman, Daniel; Rosen, M. A.; Schnall, M. D. &Yodh, A. G. “Microvascular Blood Flow Changes in Human Breast During Simulated Mammography”.
M. Chandra, D. L. Minkoff, S. S. Schenkel, S. Frangos, R. C. Mesquita, J. A. Kosty, S.Park, W. Andrew Kofke, A. G. Yodh, “Long Term Monitoring of Cerebral Blood Flow in Subarachnoid Hemorrhage Patients Using Diffuse Correlation Spectroscopy”.

PCICS Annual Meeting, Pediatric Cardiac Intensive Care Society 2012

Erin M. Buckley, Donna A. Goff, Jennifer M. Lynch, Maryam Y. Naim, Peter Schwab, Laura K. Diaz, Susan C. Nicolson, Lisa M. Montenegro, Natasha A. Lavin, Turgut Durduran, Thomas L. Spray, J. William Gaynor, Mary E. Putt, PhD, A. G. Yodh, Mark A. Fogel, Daniel J. Licht, “Sodium Bicarbonate Causes Dose-Dependent Increases in Cerebral Blood Flow in Infants and Children with Single Ventricle Physiology”.

Gordon Research Conferences, Lasers in Medicine and Biology, 2012

Busch, David R.; Choe, R.; Pathack, S.; Guo, W.; Durduran, T.; Feldman, M. D.; Mies, C.; Schnall, M. D.; Rosen, M. A.; Czerniecki, B. J.; Tchou, J.; DeMichele, A.; Putt, M. E. & Yodh, A. G, “Statistical Tumor Localization and Monitoring in Diffuse Optics”.
Regine Choe, Turgut Durduran, David R. Busch, So Hyun Chung, Saurav Pathak, Han Y. Ban, Ellen K. Foster, Tiffany Averna, Erin Buckley, Meeri Kim, Carolyn Mies, Mark Rosen, Michell Schnall, Angela DeMichele, Arjun G. Yodh, “Early Changes in Breast Cancer Blood Flow due to Chemotherapy: Potential Predictor for Therapeutic Efficacy”.

ISOTT 2011

Kejia Cai, He N. Xu, Anup Singh, Mohammad Haris, Ravinder Reddy, Lin Z. Li, “Characterizing Prostate Tumor Mouse Xenografts with CEST & MT MRI and Redox Scanning”.

Kejia Cai, Mohammad Haris, Anup Singh, Hari Hariharan, Lin Li, Ravinder Reddy, “  Blood Oxygen Level Dependent Magnetization Transfer (BOLDMT) Effect”.

ISMRM 2011

Chemical Exchange Transfer Imaging of Creatine
A. SinghM. HarisK. CaiH. Hariharan, and R. Reddy
Dependence of CEST Effect from Amine Protons of Glutamate on pH
A. SinghK. CaiM. HarisJ. H. GreenbergH. Hariharan, and R. Reddy
Fluid Suppressed T1ρ Mapping of Human Liver on Clinical Scanners
A. SinghM. HarisK. CaiW. WitscheyH. Hariharan, and R. Reddy
Modeling MT Effect of Bound Water Pool and its use in Correction of CEST Contrast for MT Asymmetry
A. SinghK. CaiM. HarisH. Hariharan, and R. Reddy
Optimized CEST Imaging of Intermediate to Fast Exchanging Agents in In-vivo Situations
A. SinghH. HariharanK. CaiM. Haris, and R. Reddy

Human Brain Mapping 2010

CMRO2 Response to Hypercapnia and Hyperoxia Measured with MRI and Diffuse Optics-
D. L. MinkoffM. N. KimE. M. BuckleyD. HanceM. TobitaJ. J WangJ. H. GreenbergJ. A. Detre, &A. G. Yodh

ISMRM 2010

A Method for De-scalping Human Brain MRI Data using Lipid Ratio Map – [[]]
A. SinghM. HarisK. CaiA. BorthakurH. Hariharan, and R. Reddy
A Study of T1p Values in Articular Cartilage Between Different Age Groups of Asymptomic Subjects – [[]]
A. SinghA. BorthakurM. SocherM. FentyE. L. McArdleW. R. WitscheyJ. LonnerJ. B. Kneelandand R. Reddy
T1p MRI and Discography Opening Pressure are Quantitative Biomarkers of Disc Degeneration In Vivo – [[]]
M. Fenty,C. M. Wang,W. R. WitscheyR. BergerP. MaurerD.M. ElliottR. Reddy and A. Borthakur
Detection of Proton Chemical Exchange between Metabolites and Water using T1p – [[]]
F. KoganW. R. WitscheyK. CaiM. Haris, and R. Reddy
Comparison of Chemical Exchange Saturation Transfer (CEST) and T1p imaging for Measurement of Proton Chemical Exchange between Metabolites and Water at 7T – [[]]
F. KoganW. R. WitscheyK. CaiM. Haris, and R. Reddy
Age Dependent Modulation of Aggrecan in Human Knee Cartilage Measured via Sodium MRI at 7T – [[]]
V.B. KasseyA. ShoreH. HariharanG. RamanathanS.N. VallespinT. ConnickA. Singh, and R. Reddy
Characterization of Blood Flow, Oxygenation and Metabolism under Hypercapnia in Swine – [[]]
W. BakerR. C. MesquitaR. S. BeesamK.V. BabuJ.H. GreenbergA.G. YodhJ.A. Detre, and R. Reddy
Longitudinal T1rho MRI of Adults with Chondromalacia following Arthroscopy – [[]]
M. FentyW. R. WitscheyA. BorthakurK. GrasleyJ. B. KneelandJ. Lonner, and R. Reddy
Quantification of Age Dependent Molecular Changes in Guinea Pig OA Model using T1rho MRI – [[]]
M. FentyV. KasseyG. DodgeA. Borthakur, and R. Reddy
Detection of Myo-Inositol in-vivo using MR Chemical Exchange Saturation Transfer Imaging (MICEST) – [[]]
M. HarisK. CaiA. SinghF. KoganW. R. Witschey 2ndH. Hariharan, and R. Reddy
Aging Effects on the Functional Connectivity in the Resting Brain -
Z. LiA. KadivarJ. PlutaH. SoaresJ. DetreM. Grossman, and Z. Wang
Magnetic Resonance Imaging of the Neurotransmitter GABA in-vivo -
K. CaiM. HarisA. SinghF. KoganH. HariharanJ. Detre, and R. Reddy
Assessment of Chemical Exchange Saturation Transfer Effects in Liver Tissue at 7T -
K. CaiM. HarisA. SinghS. GaddamD. DayeK. GrasleyG. ZsidoH. Hariharan, and R. Reddy
MRI Evaluation of a Guinea Pig Model of Arthritis -
M. Fentyet al
Negative Contrast Enhancement in T2*-weighted Images of the Human Brain During Hyperoxia -
D. Pilkintonet al
High Resolution Cerebral Blood Volume Mapping in Humans at 7T with Hyperoxic Contrast -
D. Pilkintonet al
Measurement of Cerebral Blood Flow and Cerebral Blood Volume in Humans Using Washout of Hyperoxic Contrast -
D. Pilkintonet al
Sodium MRI Multi-Echo Sequence for Simultaneous Ultra-Short Echo Imaging and T2L* Mapping at 7T with a 12 Channel Phased-Array Coil -
D. Pilkintonet al
Comparison of Baseline Signal Correction Methods for Dynamic Contrast Enhanced MRI -
Y. XueM. A. Rosen, and H. K. Song
In Vivo Quantification of Intervertebral Disc Collagen Content Using Magnetization Transfer Ratio Mapping -
C. WangW. WitscheyA. GoldbergM. ElliottJ. CalabroT. ConnickA. Borthakur, and R. Reddy
Rotating Frame, Spin Lattic Relaxation in a Swine Model of Late Ventricular Myocardial Infarction -
W. WitscheyJ.J. PillaV. FerrariK. KoolmasinghM. HarisR. HinmonG.A. ZsidoJ.H. Gorman III,R.C. Gorman, and R. Reddy
Rapid Quantification of Systolic and Diastolic Transverse T1p relaxation Times in the Human Left Ventricle -
G.A. Zsidoet al
Comparison of Baseline Signal Correction Methods for Dynamic Contrast Enhanced MRI -
Y. XueM. A. Rosen, and H. K. Song
Improved T1 mapping with Iterative Actual Flip-angle Imaging (iAFI) Technique -
Y. XueM. A. Rosen, and H. K. Song
DCE-MRI Demonstrates Antivascular Properties of Sorafenib in Metastatic Hormone-Resistant Prostate Cancer -
M. A. RosenG. AdluruR. AmaravadiY. XueJ. YuH. K. SongN. Haas, and P. O’Dwyer

ORS 2010

A Study of T1ρ Values in Articular Cartilage between Different Age Groups of Asymptomatic Subjects -
A. Singhet al
T1ρ-weighted MRI and Opening Discography Pressure are Quantitative Biomarkers of Disc Degeneration in Patients -
M. FentyR. BergerD. ElliottB. FryP. MaurerR. ReddyA. SinghC. WangJ. Yoder, and A. Borthakur

OSA BIOMED 2010

Diffuse Optical Measurements of Cerebral Blood Flow and Blood Oxygenation during Head Elevation in Healthy and Brain-Injured Adults -
M N KimT DurduranB L EdlowE M BuckleyR C MesquitaM S GradyJ M LevineJ H GreenbergJ A Detre, and A G Yodh
Optical Cerebral Hemodynamics Monitoring in Stroke Patients -
R C MesquitaT DurduranC FavillaM N KimE M BuckleyJ H GreenbergJ A DetreS E Kasner, and A G Yodh

ORA 2010

Characterization of Blood Flow, Oxygenation and Metabolism under Hypercapnia in Swine-
W.BakerR.C MesquitaR.S. BeesamV. B. KasseyJ.H. GreenbergA.G. YodhJ.A Detre, and R. Reddy

PENN CENTER FOR MUSCULOSKELETAL DISORDERS 7TH ANNUAL SCIENTIFIC SYMPOSIUM 2010

Quantitative Cartilage Degeneration Associated with Spontaneous Osteoarthritis in a Guinea Pig Model -
Matt FentyVictor KasseyGeorge DodgeWalter WitscheyAri Borthakur, and Ravi Reddy
1st Place Winner in Imaging
Predictability of Painful Discs using T1rho MRI and Disc Height in Patients with Lower Back Pain -
Rachelle (Shelly) BergerMatthew FentyBryan FryPhilip MaurerDawn Elliott, and Ari Borthakur
2nd Place Winner in Imaging

SPINE ARTHROPLASTY SOCIETY 2010

T1ρ-weighted MRI and Opening Discography Pressure are Quantitative Biomarkers of Disc Degeneration in Patients -
M. FentyR. BergerD. ElliottB. FryP. MaurerR. ReddyA. SinghC. WangJ. Yoder, and A. Borthakur